Gavi: The world's first automated vitrification instrument

Talk to embryologists about vitrification and they will readily agree that the process is both laborious and time-consuming. There is a long learning curve and intense focus required by the manual method.

At Genea, our vitrification outcomes are proven. We recently had a paper published showing that our single embryo transfer of vitrified-warmed blastocysts had equivalent live-birth rates and improved neonatal outcomes compared with fresh transfers1.

But we recognised that there was an opportunity to find a better way of achieving vitrification with greater control for new embryologists.

And to this end, we set out to find a better way of doing vitrification. From this, a completely new innovation was born: Gavi.

Greater confidence, certainty and control.

Biomedx - diagram of Gavi Pod

Perfected over five intensive years of development, Gavi approaches vitrification in an entirely different way. The key to Gavi is the Pod that holds the embryo during processing and which also acts as the container for the embryo in LN2 storage.


With extensive testing using almost 10,000 mouse embryos, we collected sufficient data to better understand the inter-relationships between the variables involved in the vitrification process. As a result we have developed Gavi with an automated, standardised protocol so that vitrification happens the same way every time.

Efficacy of Gavi


How well does Gavi perform? In pre-clinical testing, we demonstrated Gavi delivers equivalent outcomes to the manual method for mouse blastocyst stage embryos. This was recognised at oral presentations at both CRYO2 (Berlin, 2013) and ESHRE3 (London, 2013).

What about cleavage stage embryos and oocytes? We are advancing our development of cleavage stage embryo and oocyte protocols for Gavi. Our early development work on zygote and cleavage stage protocols in a mouse model was recognised as poster presentations at ASPIRE4 (Brisbane, 2014) and ALPHA5 (Antalya, 2014).

Click here for Technical Specifications 



For further information on Gavi and other Genea Biomedx products, please contact us at


1 Roy, T.K. et al., (2014). Single-embryo transfer of vitrified-warmed blastocysts yields equivalent live-birth rates and improved neonatal outcomes compared with fresh transfers. Fertil. Steril, 101:1294-1301.
2 Roy, T. K., et al., (2013). “Automated closed vitrification instrument delivers equivalent outcomes to manual open vitrification for embryos.” Oral at 3rd International Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue and Organs (CRYO), Berlin, Germany.
3 Roy, T.K., et al., (2013). “Novel automated instrument executing a standardised closed vitrification protocol yields equivalent outcomes with human blastocysts when compared with open manual vitrification system.” Human Reproduction, 28 (Suppl 1): i62-i64
4 Accepted for poster presentation at ASPIRE, The 5th Congress of the Asia Pacific Initiative on Reproduction, Brisbane, Australia 2014
5 Accepted for poster presentation at ALPHA, The 10th Biennial Conference for Scientists in Reproductive Medicine, Antalya, Turkey, 2014


Gavi is a CE marked instrument. This device will not be available for sale in US until FDA clearance is obtained. Contact us for product availability.