Genie-Plus Solution

Genie-Plus is a genome-wide sequencing solution designed to detect the inheritance of monogenic disorders (PGT-M),structural rearrangements (PGT-SR), in addition to CNV, ploidy, UPD, Sibling QC and regions of homozygosity (ROH) in preimplantation embryo biopsy samples.

Key Features

Comprehensive Detection

A single solution for combined detection of PGT-M, PGT-SR and PGT-A, including Triploidy, UPD, Sibling QC and ROH.

Genome-Wide Coverage

WGA by MDA and a patented library preparation method for better whole-genome coverage.

High Resolution

>4Mb CNVs (unknown), and >1 Mb inherited CNVs (known).

High Throughput and Scalability

40M reads/samples, 2×100 bp reads, Up to 24, 48 samples/run.

Complete PGT Analysis

Genie-Plus provides comprehensive PGT results including, Haplotype chart, CNV chart, BAF chart, ROH chart, LLR chart, Z-Score chart and Kinship analysis.